The story told in Souls in Torment begins with a well-known urban legend (a characteristic that one of the characters in the film emphasizes). Mélinton (Edgar Palomino), a young truck driver, picks up a woman on the highway who appears in the middle of the night and asks him to take her to a nearby town. He takes her and agrees to meet her the next day, later discovering that the woman in question had died a year earlier, which triggers a series of events marked by the horror of the supernatural experience.