Santos, an overweight pacheco fighter suffers from his recent divorce with La Tetona Mendoza, a voluptuous and wild female fighter. To get out of his depression, Santos begins a campaign to help Sahuayo Zombies. However, his philanthropic campaign soon becomes a very profitable business that leverages Santos for their benefit. The population becomes a zombie plague and Santos threatens to dispose of them. However, the Peyote Murderer gets rid of the zombies. But the world without zombies turns out to be worse than anyone could have imagined and the only choice to save the nation is for Santos and Peyote to work together to repopulate the world.