Ann Sothern essays the title role in My American Wife. The story opens in Smelter City, Arizona, where the richest man in town is grizzled old Indian fighter Lafe Cantillon (Fred Stone). Lafe's social-climbing sister-in-law (Billie Burke) insists that her daughter Mary wed a titled European, Count Ferdinand (Francis Lederer). Much to Lafe's delight, Mary isn't assimilated into Continental high society; instead, she instructs Count Ferdinand in the virtues of good, old-fashioned American democracy. And, of, course, the Count and Lafe become great chums when the "furriner" proves that he can ride a bucking bronco with the best of 'em.