Psychiatrist Henri Lacombe heads the National Institute of Mental Health. Day after day, his mission is to ease the suffering of his patients. His partner, Anne Beaulieu, is a consultant psychologist in a private clinic. The two deal with the ups and downs of everyday family life with their two children, Marine and William. Henri's world turns upside down the day Anne doesn't show up at the restaurant where they are supposed to meet. What happened to him?