Mano Reiji, a man who experienced a gruesome incident, is a forensic researcher at the Tokyo Metropolitan Police Department's Investigative Science Research Institute. Under the belief that "appraisal will result in the truth" and with his vast knowledge, Mano approaches cases from a view point that differs from others. On the other hand, Sawaguchi Nonna (Araki Yuko) is a rookie forensic researcher that begins working with the no nonsense Mano. They are forced to work together on a murder case.